Mar Emmanuel Giles Pothanamuzhi, C. M. I. (5 August 1932 – 6 April 2003) was a Syro-Malabar bishop.
He was born in Nadukkara, near Muvattupuzha, India. He was ordained as a priest in the Carmelites of Mary Immaculate in 1964. A botanist who lectured at Sacred Heart College, Ernakulam, he was the founder principal of Christ College, Bangalore (1969-1983) and rector of the CMI major seminary, Dharmaram College, Bangalore (1990-1996).
He was appointed as Bishop of Mananthavady (Syro-Malabar) in 1997.